منابع مشابه
Modeling the Dynamics of Second Messenger Pathways
Understanding the effect of neuromodulators requires modeling the dynamics of second messenger pathways and their effects on channel properties. Chemesis is software for modeling enzyme reactions, stoichiometric reactions, diffusion, and ligand gating of channels and is used in conjunction with GENESIS, the software program for neuronal modeling. This chapter explains the differential equations...
متن کاملActivation of second messenger pathways in alveolar macrophages by endotoxin.
The alveolar macrophage plays an important role in immune surveillance of the lung. Early responses to infectious agents by macrophages can decrease tissue injury and promote recovery of the host. Macrophage responses to pathogens are the cornerstone of the innate or nonspecific immune system. In particular, the response of macrophages to endotoxin from gram negative bacteria has been the focus...
متن کامل-Second Messenger-
Genetic polymorphisms and environmental factors work with and against each other to affect neurodevelopment and the delicate balance of neurotransmitters that underlie psychiatric disorders. This article explores the complex nature of gene-gene and gene-environment interactions and the implications for diagnosis and treatment of disease. As an example of this dynamic relationship, the gene for ...
متن کاملAntiGroupWare and Second Messenger
Organisations are called upon to make decisions almost continuously, and one of the most common models for doing so utilises a format with which most are all too familiar — gathering relevant individuals together in a meeting to discuss the issues at hand and reach a decision to be implemented. This approach seems at first glance to be an ideal strategy, but 50 years of research on the drawback...
متن کاملSecond messenger systems and adaptation.
Adaptive changes represent shifts in the equilibrium state of biologic systems in reponse to long standing alterations in their surrounding environment. Adaptation encompasses a variety of cellular changes ranging from very specific responses, such as variation in the production of a single protein, to broader responses including alterations in the rate of cell growth. It is certain that the ef...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 1993
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt0193-8c